Document Type: Original Research Papers
Department of plant protection, Agricultural Sciences and Natural Resources University, Sari
Msc. of plant protection, Agricultural Sciences and Natural Resources University, Sari
Microorganisms are important components of soil. Some soil filamentous fungi such as
Penicilium produce many bioactive small molecules, or secondary metabolites, that range from
beneficial bioactive compounds to harmful toxins. In this study, the metabolites of three
penicillium species (P. goditanum, P. moldavicum and P. corylophilum) were extracted by
adding ethyl acetate to liquid cultures. The metabolites were determined using gas
chromatography and mass spectrometry. The results obtained from the GC-MS analysis showed
that Penicillium species are sources of bioactive compounds. We have identified different
groups of compounds, such as alkaloids, alkenes, sesquiterpens, fatty acids, and essential oils.
Among them, 1,3,8-p-Menthatriene, 2-methylenecyclohexane, anthracene, neoisolongifolene,
 annulene and thioxanthene in P. goditanum, isocyclocitral, coumarin-6-ol and 2, 4, 6-
Trimethoxystyrene in P. moldavicum as well as asarone in P. corylophilum were major
compounds. Moreover, several compounds, such as oxalic acid, dibenzothiophene,
hexadecanoic acid, and alkane hydrocarbons, were identified in all species.