University of Tehran Press Progress in Biological Sciences 1016-1058 4 1 2014 05 01 Identification of biological secondary metabolites in three Penicillium species, P. goditanum, P. moldavicum, and P. corylophilum 53 61 50303 10.22059/pbs.2014.50303 EN Mohammad Ali Tajick Department of plant protection, Agricultural Sciences and Natural Resources University, Sari Hamideh Seid Mohammad Khani Msc. of plant protection, Agricultural Sciences and Natural Resources University, Sari Valiollah Babaeizad Department of plant protection, Agricultural Sciences and Natural Resources University, Sari Journal Article 2013 10 11 Microorganisms are important components of soil. Some soil filamentous fungi such as<br />Penicilium produce many bioactive small molecules, or secondary metabolites, that range from<br />beneficial bioactive compounds to harmful toxins. In this study, the metabolites of three<br />penicillium species (P. goditanum, P. moldavicum and P. corylophilum) were extracted by<br />adding ethyl acetate to liquid cultures. The metabolites were determined using gas<br />chromatography and mass spectrometry. The results obtained from the GC-MS analysis showed<br />that Penicillium species are sources of bioactive compounds. We have identified different<br />groups of compounds, such as alkaloids, alkenes, sesquiterpens, fatty acids, and essential oils.<br />Among them, 1,3,8-p-Menthatriene, 2-methylenecyclohexane, anthracene, neoisolongifolene,<br />[14] annulene and thioxanthene in P. goditanum, isocyclocitral, coumarin-6-ol and 2, 4, 6-<br />Trimethoxystyrene in P. moldavicum as well as asarone in P. corylophilum were major<br />compounds. Moreover, several compounds, such as oxalic acid, dibenzothiophene,<br />hexadecanoic acid, and alkane hydrocarbons, were identified in all species.<br /><br /> https://pbiosci.ut.ac.ir/article_50303_863334ac0882b73c159f8d0c09ab5f54.pdf