%0 Journal Article %T Effects of copper oxide nanoparticles on the growth of Chlorella vulgaris %J Progress in Biological Sciences %I University of Tehran Press %Z 1016-1058 %A Karimi, Reza %A Norastehnia, Akbar %A Abbaspour, Hossein %A Saeidi Sar, Sakineh %A Naeemi, Akram Sadat %D 2017 %\ 06/01/2017 %V 7 %N 1 %P 11-20 %! Effects of copper oxide nanoparticles on the growth of Chlorella vulgaris %K Toxicity of nanoparticles %K Percent inhibition of growth %K Specific growth rate %K photosynthetic pigments %R 10.22059/pbs.2018.226951.1253 %X The increase of copper oxide nanoparticle (CuO-NP) utilization in industry during recent years has resulted in their entry into aquatic ecosystems. In light of this fact, we have studied the toxicity of CuO-NPs at various concentrations on Chlorella vulgaris using an algal growth inhibition test (OECD201). Chlorella vulgaris was grown in positive Zander (Z-8 + N) media in a growth chamber. After reaching to the logarithmic growth phase, the algae were exposed to various concentrations of CuO-NPs at intervals of 24, 48 and 72 hours. Algal cell numbers were counted daily and the data were analyzed by Probit analysis. Some parameters such as: the effective concentration (EC10, EC50, EC90), no observed effect concentration (NOEC), specific growth rate (μ), doubling time (G) and percentage growth inhibition (I %) were calculated. The values of EC10 = 12.588, EC50 = 43.699, EC90 = 152.019 and NOEC = 4.3699 mg/L were obtained after 72 hours. The results showed significant differences between control and treatments at specified intervals of cell density and percentage of growth inhibition (P <0.05). In addition, chlorophyll and carotenoid content in treated cells were significantly lower compared to those in control samples; a decrease in the efficiency of photosynthesis is very probably a major mechanism in the reduced growth and viability of C. vulgaris exposed to CuO-NPs. %U https://pbiosci.ut.ac.ir/article_69513_de3580ca9537871f3265f78d1941b676.pdf