@article { author = {Nowruzi, Bahareh and Khavari-Nejad, Ramazan Ali and Sivonen, Karina and Kazemi, Bahram and Najafi, Farzaneh and Nejadsattari, Taher}, title = {Identification and toxigenic potential of a cyanobacterial strain (Stigomena sp.)}, journal = {Progress in Biological Sciences}, volume = {3}, number = {1}, pages = {79-85}, year = {2013}, publisher = {University of Tehran Press}, issn = {1016-1058}, eissn = {2228-7833}, doi = {10.22059/pbs.2013.32096}, abstract = {Cyanobacteria are well known for their production of a multitude of highly toxic substances . The genus Stigomena is regarded as good candidates for producing biologically active secondary metabolites, which are highly toxic to humans and other animals. The carcass of a dog was found at the shore of Lake Ali-Abad, Iran. Biomass from the discovery site appeared to be of cyanobacterial nature. We identified the strain as freshwater bloom-forming representative of the Stigomena genus on the basis of its 16S rRNA sequence. It carried the mcyE gene, as well as a potential cryptic hassallidin gene cluster. These results suggest that microcystin-induced liver damage may have significantly ontributed to the death of the dog. This case is thus the first reported incident of potential microcystin intoxication in a dog in Iran.}, keywords = {Cyanobacteria,Stigomena sp,Natural bioactive compound,Toxicity}, url = {https://pbiosci.ut.ac.ir/article_32096.html}, eprint = {https://pbiosci.ut.ac.ir/article_32096_9b43cc4961df536be57860d6d78319ab.pdf} }